A simple two-carbon compound may have been a crucial player in the evolution of metabolism before the advent of cells, according to a new study. The finding potentially sheds light on the earliest ...
Top left shows how the in vitro aggregation of the protein TDP-43 (associated with ALS), seen as white blobs, is dependent on the concentration of ATP (measured in millimolar, mM). The same is shown ...
ATP has been found to regulate cytosolic viscosity and thereby protein aggregation, which can lead to synaptic dysfunction and neurodegeneration. NMN (nicotinamide mononucleotide) is a precursor to ...
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