I still vividly remember the first time we observed neurons responding not to audible sound, but to concentrated, precisely ...

Mitochondrial calcium signaling is crucial for energy metabolism and calcium homeostasis, but monitoring it accurately is challenging due to pH fluctuations. Existing GECIs are often sensitive to pH ...

Congenital stationary night blindness (CSNB) is caused by mutations in a specific calcium channel. A comprehensive proteomic study by researchers at the University of Innsbruck now reveals how these ...

Calcium signalling is a pivotal regulatory mechanism in ciliated protozoa, orchestrating a myriad of cellular processes from ciliary beating to membrane trafficking. Recent studies have illuminated ...

The field of mathematical modelling of calcium signalling dynamics has evolved into an essential interdisciplinary area that bridges applied mathematics, computational simulation and cell biology.

In a sharp and pointy world, wound healing is a critical and marvelous process. Despite a tremendous amount of scientific study, many outstanding mysteries still surround the way in which cells in ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

This influx of calcium at the contact site attracts and activates a kinase called CaMKII, a protein known to be important in memory. CaMKII alters the plasma membrane's biochemical properties, ...

A new method exposes key details of the mechanism behind calcium signaling in prokaryotes for the first time. Working in a Listeria monocytogenes model, researchers from Umeå University (Sweden) led ...

Left: A blue light pulse of 0.1 seconds triggers a calcium signal (red) in guard cells, which is followed by an anion current (black). Right: The influx of calcium into the cell promotes the release ...