When researchers verify the effects of genes or gene–environment interactions on common diseases or age-related diseases, such as diabetes, cancer, or coronary heart disease, they usually regard age ...

Linear mixed models are increasingly used for the analysis of genome-wide association studies (GWAS) of binary phenotypes because they can efficiently and robustly account for population ...

Objectives Exposure-response trends in occupational studies of chronic disease are often modeled via log-linear models with cumulative exposure as the metric of interest. Exposure levels for most ...