Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks ...

The liver is an extraordinary organ. It detoxifies the body every day without needing a cleanse, a tea or a reset.

Scientists have published a ground-breaking study of the structure and function of a central protein in the liver: NTCP, a cellular-entry pathway for bile salts, but also for certain hepatitis viruses ...

Steatotic liver disease (commonly called fatty liver disease) progresses silently. Even in the absence of noticeable symptoms ...

The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called ...

Some high-dose detox “natural” supplements, such as green tea extract, can lead to liver inflammation, reflected in elevated ...

Fatty liver disease is rarely a standalone diagnosis: A doctor breaking the news of positive test results will probably be someone you’re already seeing for another chronic condition. It can be either ...

Discover how a miniature model of the human liver can help improve toxicology testing for food contaminants, reducing the need for animal testing.