Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD ...

Bioengineers at Queen Mary University of London have taken a significant step forward in the development of laboratory-based models of human tissues that may be used as alternatives to animal testing.

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases. The research team printed a combination of cells ...

Using their novel FRESH 3D bioprinting technique, which allows for printing of soft living cells and tissues, a lab has built a tissue model entirely out of collagen. Collagen is well-known as an ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...

Commonly, it involves a computer-assisted motorized device that deposits biocompatible materials, viable cells, growth factors, proteins, nucleic acids, drugs, and supporting components in a ...

Neural tissue engineering aims to mimic the brain's complex environment, the extracellular matrix, which supports nerve cell growth, development, and proper connectivity. This environment is carefully ...

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, ...

Single-cell RNA sequencing has transformed biology by showing which genes are active in individual cells. However, this approach requires cells to be removed from their natural environment, erasing ...