New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a ...
MET signaling's protective role shows promise for treating acetaminophen-induced acute liver failure
A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF). This pathway is shown to work as a ...
The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...
Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...
New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia ...
Instead of killing bacteria, scientists found a way to gently guide gut microbes to produce compounds linked to longevity and healthier aging.
Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...
CD47 expression levels may predict evorpacept efficacy in HER2-positive metastatic breast cancer, especially in heavily pretreated patients. Evorpacept combined with zanidatamab shows promising ...
Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...
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