A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

Immune checkpoint inhibitor (ICI) therapy before surgery for hepatocellular carcinoma (HCC) may produce major pathological ...

TLSs are highly organized structures that typically appear as clusters of B-cells containing FDCs. These clusters are then surrounded by T-cells and HEVs as shown schematically in Figure 1. We ...

Researchers have identified how to encourage tumors to build their own immune hubs—structures that look and function like lymph nodes—deep in the middle of cancer. Such immune hubs, known as tertiary ...

A team led by surgeon-scientist Dr. Vinod Balachandran identified the molecular pathway involved in the formation of tertiary lymphoid structures. Therapeutically targeting this pathway could ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

BORDEAUX, France--(BUSINESS WIRE)--TreeFrog Therapeutics has announced a research collaboration with the University of Pittsburgh focused on the potential of tertiary lymphoid structures (TLS) in ...

Association between PD-1 expression on tumor-infiltrating regulatory T cells and resistance to first-line nivolumab in advanced clear cell renal cell carcinoma: Insights from the HCRN GU16-260 ...