This is a preview. Log in through your library . Abstract The history of the relationship of biological activity to partition coefficient and related properties is briefly reviewed. The dominance of ...

BMC Clin Pharmacol. 2010;10:1-27. It is assumed that the tissue consists of N capillaries/cm 3, all with exactly the same geometry, blood flow, permeability, etc. It is also assumed that the relation ...

New partitioning coefficients of first-transition row elements, Ga and Ge between olivine and silicate melt have been reported. New high-temperature experiments have investigated the effects of oxygen ...

BMC Clin Pharmacol. 2010;10:1-27. One can use this value of PS to estimate the "equivalent" thickness of the rat blood-adipose diffusion limiting barrier. The permeability is equal to: where D W is ...