Once in every cell cycle microtubules become organized into a bipolar spindle that segregates the replicated chromosomes to the two daughter cells 1,2. Two models, which are not mutually exclusive, ...

Scientists have gained new insight into the formation of the spindle, which is the molecular machine that divides up genetic material prior to cell division. Their work focuses on the motor protein, ...

The orientation of cell division is tightly regulated to ensure proper tissue morphogenesis and to prevent cancerous growth. Cell division can be symmetric resulting in two equal daughter cells and ...

Cambridge, Mass. - April 26, 2012 - The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests, according to ...

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a signaling pathway that restricts cleavage furrow formation to the mid-plane of the cell. Cell division is a ...

Researchers have identified a novel protein that plays a crucial role in the formation of the mitotic spindle, which is essential for correct segregation of a full set of chromosomes to each daughter ...